How Low Cholesterol Worsens Menopause & Decreases Longevity

June 12, 2025 6 min read

How Low Cholesterol Worsens Menopause & Decreases Longevity

Disclaimer: This article is purely informational and makes no claims as to treatment or cure by or from any supplement or program BodyHealth may offer. If you or someone you know has any heart condition, we recommend you see a doctor trained in functional medicine to help you locate the cause of the condition and recommend a solution for it.

Before we cover exactly how menopause and perimenopause work in the Menopause Series, I want to cover something that affects this area significantly due to the amount of false information currently existing on the subject.

This is information that leads to choices which can make menopause worse, or harder to deal with, as well as lower our overall longevity.

I'm talking about the subject of cholesterol.

As perimenopause and menopause have everything to do with a lowering of key hormones that occurs, this becomes quite important. Because cholesterol is what these key hormones are made from.

You’ve probably heard of the Cholesterol Hypothesis: that higher levels of cholesterol, particularly LDL Cholesterol, are associated with higher rates of Heart Disease.

And, to lower cholesterol levels in order to prevent heart disease, we must take drugs known as statins that lower our liver’s ability to produce cholesterol, as well as cut down on high cholesterol foods, thus lowering overall cholesterol levels.

This hypothesis has been so deeply ingrained in our understanding of how the body works that for decades no one challenged it.

There's just one thing: during this same amount of time no one has proven it to be true either.

In fact, the only studies we have on the matter not only refute it, but actually show that more often than not, the situation is the opposite.

When cholesterol levels are lowered mortality rates from cardiovascular disease do not decline, they actually increase.

It's when cholesterol levels rise that mortality rates come down.

And this is not just a contrarian idea: in a study of 12.8 million adults, it was found that the lowest risk of heart disease and highest potential of survival was in the 200 to 240 levels of total cholesterol.

And this has everything to do with menopause and perimenopause.

You see, during perimenopause, and much more during menopause and after, levels of the hormones estrogen, progesterone and testosterone decrease in women.

They start to fluctuate during perimenopause and then drop very low during menopause.

And it's the dropping of these hormones that cause the majority of issues women experience here: hot flashes, loss of bone mass and lean muscle, mood changes, risk of heart attack, sleep issues and more.

Well, these hormones are made from cholesterol.

And if we start artificially lowering our cholesterol levels, we lower the amount of these hormones our body can produce not only during perimenopause and menopause, but also before, setting us up to have a harder time when we do hit this transition.

So let's dive in and see what cholesterol actually is (most people don't know), how it actually works, and what is actually to blame for the troubles being assigned to cholesterol.


WHAT IS CHOLESTEROL?


Cholesterol is one of the most important chemicals in your body.

It’s necessary in building the membrane of your cells, producing vitamin d, and supporting your metabolism.

Key hormones such as estrogen, progesterone and testosterone are also made from it, and levels of these hormones will be very low if cholesterol production is low.

It’s also vital to your cell’s ability to produce energy.

And it’s part of your body’s solution for injured blood vessels, which we’ll get to.

But most people have heard that there’s good and bad cholesterol. Good being HDL and bad being LDL.

Actually, there aren’t two different kinds of cholesterol, only one: Cholesterol.

Here’s how it works:

Cholesterol is made by the liver.

The liver then packages the cholesterol in a protein called a Low Density Lipo-Protein (LDL) and sends it to the cells where it's needed.

Then, when the cell is finished with the cholesterol, it packages it in another protein called a High Density Lipo-Protein (HDL) which sends it back to the liver to be broken down and gotten rid of.

The proteins HDL and LDL are just transportation proteins, nothing more.

Both are needed, but cholesterol is just cholesterol.

So where does heart disease come in?


WHY IS CHOLESTEROL LINKED TO HEART DISEASE?


Now we get to the crux of the matter.

The rationale behind cholesterol being the cause of heart disease has to do with cholesterol building up in your arteries, clogging them so they are narrower, and making it harder for blood cells to pass through.

About 25% of our blood vessels are actually smaller in diameter than the blood cells trying to pass through them. So these blood cells have to squish down and elongate to make it through.

If something like cholesterol is added, the passageway becomes more narrow, so it’s harder for them to get through.

This causes your heart to have to beat harder to try to shove the blood cells through this narrowed passage.

So this is true, cholesterol added here does clog these blood vessels.

But... the cholesterol isn't there because you ate cholesterol. (Cholesterol you eat, if unneeded, is just broken down and gotten rid of by the liver. It’s the liver that makes almost all of the cholesterol that is actually used in our body.)

And this is important, because if we don’t spot this, then we won’t see what’s actually causing the problem here. And there is a very real problem.

This is a case of the cart coming before the horse.

When toxins are in your blood stream: trans fats, herbicides, high levels of processed sugars — these things injure the walls of your blood vessels.

This is a real injury, much like a scraped knee.

And when you scrape your knee your body puts a sort of bandage on it, right? A scab made of blood cells.

Well, your blood vessels have a bandage the body puts on them when they become injured. And that bandage is made of cholesterol.

So maybe you’re consuming high levels of sugar. Sugar causes inflammation to blood vessels, which is why it needs to be cleared out fast.

But you’re eating so much sugar that your body has trouble clearing it out and it stays in your blood vessels longer than it should.

Over the years, along with trans fats and other toxins, this causes injuries to our blood vessels.

So your body needs to put bandages on these points.

So it sends cholesterol to cover them up.

But look at this now. The cholesterol is put there because something injured the blood vessel, not just because you ate cholesterol-rich food.

Even if you removed all cholesterol-rich food from your diet, your liver would still produce cholesterol to put on an injured blood vessel.

It has to.

And that’s what the statins block. They poison your liver’s ability to produce as much cholesterol so less is going to bandage these injuries.

But then the injuries aren’t bandaged and get worse, and they can still lead to a heart attack. Because high blood pressure is only one of the things that can contribute to that, there are much more.

But we’ll cover that in the next article.

Now, these injuries may have gotten so bad that on an immediate basis, while we work to heal them, we need to take statins. Maybe.

But we need to know the actual cause here or we’ll fixing something that isn’t broken and not fixing what is.

The real solution to prevent high blood pressure is to lower toxins in our body, lower sugar levels, especially processed sugars, remove harmful bacteria in our blood stream (yes, it gets in there), raise omega 3 levels (makes the blood cells squishier so it’s easier for them to pass through) — but not to lower the cholesterol that your body needs to survive.

During the Fat Loss Program you may find that your cholesterol levels rise… and that you are feeling better and better.

This is fine. This is good.

Your blood flow is better, your cells are healthier, your body is able to make the hormones it needs to properly function.

However, if you have any real worry, ask to have your inflammation markers tested.

If those are high, then yes, there is a problem that needs to be addressed, because the high inflammation means there is injury to blood vessels to one degree or another.

But it won’t be prevented by lowering cholesterol. It will be prevented by removing from your body those things causing the inflammation.

But the raising of cholesterol levels on their own, without a rise in inflammation, is healthy and actually necessary when we seek to improve muscle mass, balance hormones, increase testosterone levels, increase overall health and energy (cholesterol is necessary for energy production too), and increase longevity.

Of course, always check with your primary care physician and follow their advice.

But we want you the healthiest you can possibly be.

In the next article we’ll dive into the actual causes of heart disease, and how to prevent and reverse those causes over time.

I hope this helps.


REFERENCES:

1. Lack of an association or an inverse association between low-density-lipoprotein cholesterol and mortality in the elderly: a systematic review

2. Total cholesterol and all-cause mortality by sex and age: a prospective cohort study among 12.8 million adults


*These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.